ncRNA name | NFAT5 siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | RPE cells, Müller cell line: MIO-M1 |
Methods | qRT-PCR, BrdU incorporation assay, Western blot, siRNA transfection |
Expression pattern | associated |
Functional description | Knockdown of NAFT5 or inhibition of AR decreased the cell viability under hyperosmotic (but not hypoxic) conditions and aggravated the hyperosmotic inhibition of cell proliferation. |
PubMed ID | 27628063 |
Year | 2016 |
Title | Osmotic expression of aldose reductase in retinal pigment epithelial cells: involvement of NFAT5. |
Drug-related ncRNA | NO |
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