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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name NFAT5 siRNA
ncRNA Category siRNA
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line RPE cells, Müller cell line: MIO-M1
Methods qRT-PCR, BrdU incorporation assay, Western blot, siRNA transfection
Expression pattern associated
Functional description Knockdown of NAFT5 or inhibition of AR decreased the cell viability under hyperosmotic (but not hypoxic) conditions and aggravated the hyperosmotic inhibition of cell proliferation.
PubMed ID 27628063
Year 2016
Title Osmotic expression of aldose reductase in retinal pigment epithelial cells: involvement of NFAT5.
Drug-related ncRNA NO

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